SimulaTE: simulating complex landscapes of transposable elements of populations

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SimulaTE: Simulating complex landscapes of transposable elements of populations.

Motivation Estimating the abundance of transposable elements (TEs) in populations (or tissues) promises to answer many open research questions. However, progress is hampered by the lack of concordance between different approaches for TE identification and thus potentially unreliable results. Results To address this problem, we developed SimulaTE a tool that generates TE landscapes for populat...

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A model of the evolution of a transposable element family in a Mendelian host population is proposed that incorporates heritable phenotypic mutations in the elements. The temporal behavior of the numbers of mutant and wild-type elements is studied, and the expected extinction time of the transposable element family is examined. Our results indicate that, if the mutant can be transposed equally ...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2018

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btx832